Rescheduled: We will be performing system upgrades from Friday, July 19 at 2:00 p.m. ET to Monday, July 22 at 8:00 a.m. ET.
Please note that during that time you will not be able to login to your account and place orders.
Phos Choline

Phos Choline

Order Code: 10526

SRP $23.27
Overview

Lecithin-derived phospholipid formula
• Provides 2880 mg of phosphatides per daily dose
• Supports liver health

Phos Choline provides phospholipids that help to support liver function. Phosphatidyl-choline (PC) is the primary phospholipid (also known as phosphatide) found in lecithin.1
It is an important component of cell membranes and is highly concentrated in hepatocytes.2,3 All lipoproteins are rich in PC, and are primarily produced in the liver.3 Normal PC levels may help to prevent hepatic lipid accumulation as PC is necessary for the production and secretion of very low density lipoproteins (VLDL), which transport triglycerides from the liver.2,3 PC deficiencies may lead to VLDL and triglyceride buildup in the liver, which negatively affects liver function and health.3 Recent in vitro studies show that hepatocytes also overproduce free radicals when grown in choline deficient medium; excess reactive oxygen species production can lead to DNA damage and impair liver function.4 In a randomized, double blind trial, 57 healthy adults were fed diets low in choline. After six weeks of depletion, fatty liver, liver damage and/or muscle damage was observed among 68% of participants.5 When choline was replenished in the diet, the organ dysfunction was resolved in all participants within six weeks.5

 

REFERENCES
1. Patterson KY, Bhagwat SA, Williams JR, Howe JC, Holden JM. January 2008 (http://www.ars.usda.gov/SP2UserFiles/Place/80400525/Data/Choline/Choln02.pdf).
2. Duric, M, Sivanesan, S, Bakovic, M. Eur. J. Lipid Sci. Technol. 2012; 114: 389–398.
3. Cole, LK, Vance, JE, Vance, DE. Biochimica et Biophysica Acta. 2012; 1821: 754–761.
4. Zeisel, SH. Mutation Research. 2012; 733: 34– 38.
5. Fischer, LM, daCosta, KA, Kwock, L, Stewart, PW, Lu, TS, Stabler, SP, Allen, RH, Zeisel, SH. Am J Clin Nutr. 2007; 85: 1275–85.

Read More Read Less
Information
Product Code 10526
Brand Genestra Brands
Health Functions Liver Health
Category Essential Fatty Acids & Phospholipids
System Digestive System
Key Ingredients Calories, Calories from Fat, Soy Lecithin
NPN 80006244
size 90 caps
Format Capsules
Allergen-Free Formula
  • Dairy Free
  • Gluten Free
Reviews

Leave a review