Probiotic to support healthy weight management
- Assists in weight management when used with a program of reduced intake of dietary calories and increased physical activity
- Includes a combination of five proprietary human strains clinically studied in adults
- Supports gastrointestinal health and promotes a favourable gut flora
- Provides 50 billion CFU per capsule
HMF® Metabolic was specifically formulated with a combination of five proprietary probiotic strains, which were studied in a recent randomized, double-blind, placebo-controlled trial in adults.1 Results of the study demonstrated that HMF® Metabolic’s probiotic strains significantly increased quality of life scores, including general wellness and state of health.1 These strains have also been examined in various other preclinical and clinical studies for their beneficial health effects, including their ability to promote a healthy gut flora composition.2-6 Emerging research demonstrates that diet and weight play an important role in the composition of the intestinal microflora, with the typical Western diet and larger body composition being associated with a greater proportion of Firmicutes than Bacteroidetes.7 These alterations in the normal gut flora composition may impact intestinal function, including short-chain fatty acid production and energy metabolism.8 Available in a convenient, once-daily capsule format, HMF® Metabolic can be easily added to any lifestyle regimen to support overall health and an optimal gut flora composition.
span style="font-size: xx-small;">1. Michael, DR, Jack, AA, Masetti, G, Davies, TS, Loxley, KE, et al. Sci. Rep. 2020; 10: 4183.
span style="font-size: xx-small;">2. Michael, DR, Moss, JW, Calvente, DL, Garaiova, I, Plummer, SF, Ramji, DP. Benef Microbes. 2016;7(3):443-51.
span style="font-size: xx-small;">3. Michael, DR, Davies, TS, Moss, JWE, Calvente, DL, Ramji, DP, et al. Sci Rep. 2017 Jun 6;7(1):2883.
span style="font-size: xx-small;">4. Williams, EA, Stimpson, J, Wang, D, Plummer, S, Garaiova, I, Barker, ME, Corfe, BM. Aliment Pharmacol Ther. 2009; 29(1): 97-103.
span style="font-size: xx-small;">5. Madden, JA, Plummer, SF, Tang, J, Garaiova, I, Plummer, NT, Herbison, M, Hunter, JO, Shimada, T, Cheng, L, Shirakawa, T. Int Immunopharmacol. 2005; 5(6): 1091-1097.
span style="font-size: xx-small;">6. Plummer, SF, Garaiova, I, Sarvotham, T, Cottrell, SL, Le Scouiller, S, Weaver, MA, Tang, J, Dee, P, Hunter, J. Int J Antimicrob Agents. 2005; 26(1): 69-74.
span style="font-size: xx-small;">7. Kobyliak, N, Conte, C, Cammarota, G, Haley, AP, Styriak, I, et al. Nutr Metab (Lond). 2016; 13:14.
span style="font-size: xx-small;">8. Cerdó, T, García-Santos, JA, Bermúdez, MG, Campoy, C. Nutrients